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Benzathine benzylpenicillin – 10 g,
Procaine benzylpenicillin – 10 g,
Dihydrostreptomycin sulfate – 16,4 g.
The synergistic bactericidal action of the penicillin-dihydrostreptomycin association covers a very wide spectrum of microorganisms. Penicillin attacks bacterial cell walls and thus enhances the penetration of dihydrostreptomycin which interferes w/ the protein synthesis. Penicillin G is active against many G(+) bacteria. Its distribution is wide. The benzathine form of penicillin G is active for 18-24 hrs and the procaine form gives an extended action up to 5 days (3 days in practice). Dihydrostreptomycin is mainly active against G(-) bacteria and thus completes the spectrum of penicillin G.
Indications for use specifying the target species
Cattle: Pasteurellosis pneumonia, septicemia, metritis, leptospirosis and reticulo-peritonitis.
Swine: Septicemia, MMA syndrome, erysipelas, leptospirosis, prevention and treatment of respiratory diseases.
Sheep/goats: Vesicular stomatitis, arthritis and septicemia.
For IM injection.
Cattle, pigs and horses: 1 inj of 5-10 mL/100 kg BW every 3 days.
Calves, foals, piglets, small animals: 1 inj of 1-2 mL/25 kg BW every 3 days.
Contraindications: Use with care to animals sensitive to penicillin. Do not administer to rabbits.