Catosal 10% (Butaphosphan + Vitamin B12) 100ml – Metabolic Stimulant & Tonic for Cattle, Horses, Pigs, Dogs & Cats

What Is Catosal 10%?

Catosal 10% is an injectable metabolic stimulant and tonic manufactured by Bayer Animal Health. Each ml contains two synergistic active ingredients: butaphosphan 100 mg (an organic phosphorus compound) and cyanocobalamin 0.05 mg (vitamin B12). Together, they form a clear pink solution that supports cellular energy metabolism, stimulates protein and fat metabolism, promotes glycogen formation, enhances immune resistance, and supports recovery in sick, weakened, or nutritionally depleted animals.

Catosal is suitable for a wide range of species: cattle, horses, pigs, sheep, goats, dogs, cats, fur animals and poultry. It is one of the most widely used metabolic support injections in veterinary medicine worldwide.

One of its most significant advantages: zero-day withdrawal period for meat, milk, and eggs — making it safe to use in food-producing animals at any stage without requiring the animal to be withheld from slaughter or milking.

How Catosal Works — The Two Active Ingredients

Butaphosphan (100 mg/ml)

Butaphosphan is an organic phosphorus compound that provides 17.3 mg of bioavailable phosphorus per ml. Unlike inorganic phosphate supplements, butaphosphan is rapidly absorbed and utilised at the cellular level. Phosphorus is critical for ATP (adenosine triphosphate) synthesis — the primary energy currency of every cell. By replenishing phosphorus availability, butaphosphan directly stimulates cellular energy production, supports gluconeogenesis and glycogen formation, and improves muscle contractility and neural function. It is particularly effective in cases of metabolic stress, postpartum disease, and hypocalcemia (milk fever), where cellular energy demand is acutely elevated.

Cyanocobalamin — Vitamin B12 (0.05 mg/ml)

Cyanocobalamin is the injectable form of vitamin B12, essential for red blood cell production (haematopoiesis), myelin sheath synthesis, and the metabolism of proteins, carbohydrates and fats. B12 deficiency leads to anaemia, neurological symptoms, poor growth, and reproductive failure. When administered by injection, cyanocobalamin achieves plasma levels far superior to oral supplementation, making Catosal particularly valuable in animals with digestive conditions limiting enteral absorption.

Together, butaphosphan and cyanocobalamin have a synergistic effect: phosphorus activates metabolic pathways while B12 supports the cellular machinery needed to carry out those processes — increasing each other’s clinical effectiveness.

Indications — What Catosal Is Used For

Cattle

• Anorexia, weight loss, and general debility
• Hypocalcaemia (milk fever) and tetanic syndromes — adjunct therapy
• Postpartum diseases: retained placenta, metritis, ketosis, exhaustion after calving
• Reduced dairy performance and impaired fertility
• Prevention of white muscle disease in calves
• Secondary anaemias, including those associated with parasitism
• Stimulation of growth and development in calves
• Adjunct in treatment of infertility and metaphylaxis to enhance breeding success

Horses

• Lumbago (azoturia/tying-up) — recovery and prevention
• Anorexia and performance loss
• Anaemia and post-illness recovery
• Increasing strength, endurance and stamina in sport and working horses
• General metabolic support and tonic during intensive training

Pigs

• Metabolic disorders caused by poor nutrition or disease
• Stimulation of growth in piglets and weaners
• Support in MMA syndrome recovery (mastitis-metritis-agalactia in sows)
• Exhaustion and weakness in sows after farrowing
• Anaemia and poor condition in growing pigs

Sheep & Goats

• Metabolic disorders: pregnancy toxaemia (twin lamb disease), milk fever
• Anaemia associated with helminthiasis and blood loss
• Postpartum weakness and recovery support
• Stimulation of growth in lambs and kids

Dogs

• Convalescence and recovery from acute and chronic disease
• Metabolic disorders, tetany, paresis
• Secondary anaemias
• States of exhaustion and emaciation
• Increasing performance in working dogs
• Supporting growth in young dogs and puppies
• Stimulating immunity and resistance to disease

Cats & Fur Animals

• Recovery from illness, surgery or severe debilitation
• Anaemia and nutritional deficiency states
• Metabolic support in kittens and growing young animals

Poultry (Drinking Water)

• Growth stimulation and acceleration of development
• Reduction and support during moulting
• Prevention of cannibalism behaviours
• Recovery from disease stress

Dosage Table

Give by subcutaneous (SC), intramuscular (IM), or intravenous (IV) injection. For cattle, IV is preferred. IV for cattle; IV, IM or SC for all other species. Volumes over 10 ml should be split across multiple injection sites.

For chronic conditions and use as a general tonic in healthy animals, administer half the acute dose. Repeat after 5–14 days if necessary.

Combination Therapy

Catosal is compatible with antibiotic treatment — it does not interfere with antibacterial drugs and can be used concurrently. It can also be mixed with glucose solution or calcium solutions for combination metabolic support therapy, making it a valuable adjunct in drip therapy for downer cows, post-surgical recovery, and intensive care situations.

Withdrawal Period

Catosal has a zero-day withdrawal period for meat, milk and eggs. This makes it one of the very few injectable veterinary products that can be safely administered to dairy cows, milking ewes, and laying hens without any requirement to discard milk, hold back slaughter, or withdraw eggs from sale.

Contraindications & Safety

• Do not use in animals with known hypersensitivity to any component of the product
• Do not administer to rabbits whose meat is intended for human consumption
• No known interactions with other medications — compatible with concurrent antibiotic therapy
• No adverse effects described at recommended dosages; rare allergic reactions at the injection site possible
• Safe for use during pregnancy and lactation

Storage & Shelf Life

• Store in a dry, dark place at 5–25°C — do not freeze
• Shelf life unopened: 5 years from date of manufacture
• After opening: use within 28 days
• Sterile 10% solution in hermetically sealed 100ml glass vial

Frequently Asked Questions

What is butaphosphan and why is it better than regular B12 injections?

Butaphosphan is an organic phosphorus compound that directly fuels cellular ATP energy production — something plain B12 injections don’t provide. Catosal combines both: butaphosphan for immediate energy metabolism support, and cyanocobalamin (B12) for blood cell production and protein metabolism. The two are synergistic — making Catosal significantly more effective for metabolic recovery than either component alone.

What is Catosal used for in dogs?

In dogs, Catosal is used for recovery from illness, surgery or prolonged disease, secondary anaemia, metabolic disorders, exhaustion, paresis, and tetanic syndromes. It is also used to boost performance and resistance to disease in working dogs, and to stimulate growth and development in puppies. The recommended dose for dogs is 0.5–5 ml depending on size, given SC, IM or IV.

What is the Catosal dose for cattle?

Adult cattle receive 10–25 ml by intravenous injection for acute conditions. Calves receive 5–12 ml IV. For chronic conditions or general tonic use, halve these doses. Repeat daily in acute cases, or every 1–2 weeks as a stimulant. Catosal is particularly effective in cattle for milk fever adjunct therapy, ketosis recovery, retained placenta, and fertility stimulation.

Can Catosal be used in dairy cows while milking?

Yes. Catosal has a zero-day milk withdrawal period, meaning treated cows can continue to be milked for human consumption immediately after administration. This is one of its key practical advantages for dairy farmers.

Can Catosal be given alongside antibiotics?

Yes. Catosal is fully compatible with antibiotic treatment and can be administered concurrently. It is frequently used as a supportive metabolic adjunct alongside antibiotics in cases of respiratory disease, mastitis, metritis, and postpartum infections in cattle.

How quickly does Catosal work?

Initial metabolic effects from butaphosphan are typically seen within 24–72 hours of injection. For anaemia and B12-related deficiencies, improvement in red blood cell parameters may take several days to weeks depending on the severity. In animals with acute metabolic crises (e.g. downer cows, ketosis), marked improvement is often visible within 12–24 hours when used alongside appropriate supportive therapy.

What is the shelf life of Catosal after opening?

Once the vial is opened, Catosal should be used within 28 days. The unopened shelf life is 5 years. Store at 5–25°C and do not freeze.

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