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| NexGard Combo | Single Dose Volume (ml) | Esafoxolaner (mg) | Eprinomectin (mg) | Praziquantel (mg) |
|---|---|---|---|---|
| Cats 0.8–<2.5 kg | 0.3 | 3.60 | 1.20 | 24.90 |
| Cats 2.5–<7.5 kg | 0.9 | 10.80 | 3.60 | 74.70 |
Target species: Cats.
For cats with or at risk of mixed infections with cestodes, nematodes, and ectoparasites. This veterinary medicinal product is specifically indicated when all three parasite groups need to be treated simultaneously.
Gastrointestinal nematodes
Cardiopulmonary nematodes
Urinary nematodes
Do not use in cases of hypersensitivity to the active substances or to any of the excipients.
Increased salivation, diarrhoea, transient skin reactions at the application site (alopecia, pruritus), anorexia, lethargy, and vomiting have been rarely observed in clinical studies shortly after administration. These were predominantly mild, short-lived, and self-limiting.
The frequency of adverse reactions is defined by the following classification:
Route of administration: Spot-on application.
The recommended minimum doses are 1.44 mg esafoxolaner, 0.48 mg eprinomectin, and 10 mg praziquantel per 1 kg body weight. Select the appropriate applicator size based on the cat’s body weight.
| Cat Body Weight | Single Dose Volume (ml) | Esafoxolaner (mg) | Eprinomectin (mg) | Praziquantel (mg) |
|---|---|---|---|---|
| 0.8–<2.5 kg | 0.3 | 3.60 | 1.20 | 24.90 |
| 2.5–<7.5 kg | 0.9 | 10.80 | 3.60 | 74.70 |
| ≥7.5 kg | Appropriate combination of applicators | |||
For the treatment of flea and/or tick infestations and/or ear mites, combined with simultaneous treatment of gastrointestinal and/or pulmonary and/or urinary nematodes and cestodes, a single dose of the product should be applied. The need and frequency of treatment(s) should be determined in consultation with the responsible veterinarian, taking into account the local epidemiological situation and the animals’ lifestyle (i.e. outdoor access).
Areas free of heartworm (Dirofilaria immitis):
Cats not continuously at risk of heartworm infection should be treated according to the schedule prescribed by the veterinarian and adapted to each individual re-infestation situation. Otherwise, a narrower-spectrum product should be used to provide sustained treatment against the relevant parasites.
Heartworm-endemic areas:
Cats living in heartworm-endemic areas and identified as hunters may be treated at monthly intervals to provide appropriate prevention and treatment of potential cestode re-infestation. Otherwise, a narrower-spectrum product should be used for further treatment. Heartworm prophylaxis through elimination of Dirofilaria immitis larvae should begin within 1 month of the first expected exposure to mosquitoes and should continue for at least 1 month after the last mosquito exposure.
Ear mites:
For ear mites, a follow-up veterinary examination should be conducted 4 weeks after treatment to determine whether additional treatment with a narrower-spectrum product is necessary.
Store unused applicators in the original packaging to protect from light. Used applicators must be disposed of immediately.
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