Easotic Ear Drops for Dogs – Gentamicin, Miconazole & Hydrocortisone Aceponate Otic Suspension

Easotic is a prescription ear drop suspension for dogs manufactured by Virbac, combining three powerful active ingredients in one product to treat the infection, the fungal overgrowth, and the inflammation of canine otitis externa (ear infections) simultaneously.

Each ml contains:

  • Hydrocortisone aceponate (HCA) — 1.11 mg/ml (potent anti-inflammatory corticosteroid)
  • Miconazole nitrate — 15.1 mg/ml (broad-spectrum antifungal)
  • Gentamicin sulfate — 1,505 IU/ml (aminoglycoside antibiotic)

Supplied as a 10ml multi-dose bottle with a unique pump delivery system — one pump delivers exactly 1ml every time, with no risk of contamination.

What is Otitis Externa?

Otitis externa is an inflammation of the outer ear canal and is one of the most common reasons dogs visit the vet. It’s often caused by a combination of bacteria (particularly Staphylococcus pseudintermedius) and yeast (Malassezia pachydermatis), accompanied by redness, swelling, discharge, bad odour, and intense itching or pain.

Dogs with floppy ears (Cocker Spaniels, Labradors, Basset Hounds), allergies, or those that swim frequently are especially prone to ear infections.

How Easotic Works – Triple-Action Formula

Easotic tackles ear infections from three angles simultaneously:

1. Gentamicin (Antibiotic):
An aminoglycoside antibiotic that kills bacteria by inhibiting protein synthesis. Particularly effective against the most common ear pathogens including Staphylococcus pseudintermedius, Pseudomonas, and Proteus species. Well tolerated with no toxic effect on the middle ear structures.

2. Miconazole (Antifungal):
A synthetic imidazole antifungal that destroys yeast and fungi by blocking ergosterol synthesis in their cell membranes. Especially effective against Malassezia pachydermatis, the primary yeast involved in canine ear infections. Also has bactericidal activity against gram-positive bacteria.

3. Hydrocortisone Aceponate – HCA (Anti-inflammatory):
A diester glucocorticosteroid that is 60 times more lipophilic (fat-soluble) than standard hydrocortisone, meaning it penetrates deep into the skin of the ear canal for potent local anti-inflammatory and anti-itch action. Crucially, once HCA reaches systemic circulation, it has already been converted to a much weaker metabolite — delivering high local potency with minimal steroid side effects.

Indications

Easotic is indicated for the treatment of:

  • Acute otitis externa in dogs
  • Acute exacerbation of recurrent otitis externa

Specifically, infections associated with bacteria susceptible to gentamicin and fungi susceptible to miconazole, in particular Malassezia pachydermatis and Staphylococcus pseudintermedius.

Dosage and Application

Dose: 1ml (one pump) per affected ear, once daily, for 5 days.

This is a fixed dose regardless of dog size — no need to calculate by weight or count drops.

Step-by-Step Application

  1. Clean the ear: Gently clean and dry the external ear canal. Trim excess hair around the ear opening
  2. Shake the bottle well before each use
  3. Prime the pump (first use only): Depress the pump 1–2 times to fill the clear cannula with product
  4. Insert the cannula carefully into the affected ear canal
  5. Deliver one pump (1ml) of suspension
  6. Gently massage the base of the ear to distribute the medication
  7. Repeat for the other ear if both are affected
  8. Wash hands after use

Key Benefits

  • Unique pump system: Delivers exactly 1ml every time, from any angle, with no contamination risk — no counting drops
  • Simple 5-day course: One pump per ear, once daily, for just 5 days. Shorter than most ear treatment courses
  • Persistent activity: Antimicrobial and anti-inflammatory effects continue for 7–10 days after the treatment course finishes
  • Triple-action: Antibiotic + antifungal + anti-inflammatory in a single product
  • Minimal steroid side effects: HCA delivers high local potency while being rapidly inactivated systemically
  • Soft, flexible nozzle: Comfortable and safe delivery into the ear canal
  • Universal dosing: Same dose for all dog sizes — no weight-based calculations

Side Effects

  • Transient local reactions at the injection site (mild irritation)
  • Hearing loss has been reported in rare cases — immediately discontinue if any hearing loss or balance problems are observed
  • Long-term use of topical corticosteroids can cause adrenocortical suppression — use only for the prescribed 5-day course

Contraindications and Warnings

  • Do not use if the eardrum (tympanic membrane) is perforated or suspected to be damaged — this is critical. Using Easotic with a ruptured eardrum can cause ototoxicity (damage to hearing and balance structures)
  • Do not use in dogs with known hypersensitivity to corticosteroids, aminoglycoside antibiotics, or imidazole antifungals
  • For dogs only — do not use in cats
  • Do not use in breeding dogs, pregnant, or lactating bitches (safety not established)
  • Do not use concurrently with calcium channel blockers (e.g., diltiazem, amlodipine)
  • Use with caution in dogs with liver disease (miconazole is metabolised hepatically)
  • Compatibility with ear cleaners has not been demonstrated — clean ears before applying Easotic, not simultaneously
  • Do not mix with other ear medications

Storage

Store at room temperature (below 25°C). Discard unused product 10 days after first opening. Do not freeze. Keep out of reach of children.

Frequently Asked Questions

How long does it take for Easotic to work?
Most dog owners notice a significant improvement within 2–3 days. The full 5-day course should always be completed. The medication continues working for 7–10 days after the last application.

Is Easotic the same dose for all dogs?
Yes. One pump (1ml) per affected ear, regardless of dog size. This is one of Easotic’s major advantages over other ear drops.

Do I need to clean my dog’s ears before applying?
Yes. Gently clean and dry the ear canal before the first application. Do not use ear cleaners at the same time as Easotic — clean first, then apply.

Can Easotic be used in cats?
No. Easotic is licensed for dogs only. For feline ear infections, consult your veterinarian for appropriate alternatives.

What if my dog’s ear infection doesn’t improve?
If there is no improvement after the 5-day course, or if the infection recurs, contact your veterinarian. Further diagnostic evaluation (culture and sensitivity testing) may be needed.

How long does the bottle last after opening?
The opened bottle must be discarded after 10 days. The 10ml bottle typically provides enough for a full 5-day course for both ears.

Is Easotic safe if my dog has a ruptured eardrum?
No. Easotic must never be used if the eardrum is perforated or suspected to be damaged. Your vet should examine the eardrum before prescribing Easotic.

How does Easotic compare to Otomax / Surolan?
All three are combination ear drops containing an antibiotic, antifungal, and corticosteroid. Easotic’s key advantages are its unique pump delivery system (no counting drops), the shorter 5-day course (vs 7–14 days for others), and HCA’s superior local-to-systemic potency ratio.

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