Procox Oral 18 mg/ml Toltrazuril 7.5 ml


Active Substances

Procox contains 0.9 mg / ml emodepside and 18 mg/ml toltrazuril.

Excipients:

0.9 mg / ml of butylhydroxytoluene (E321 as an antioxidant)

0.7 mg / ml sorbic acid (E200 as preservative)



THERAPEUTIC INDICATIONS

For dogs, suspected or mixed parasitic invasions of roundworms and coccidia of the following species:

Roundworms: – Toxocara canis (adult adults, immature adults, L4) – Uncinaria stenocephala (mature adults) – Ancylostoma caninum (mature adults) – Trichuris vulpis (mature adults)

Coccidia: – Isospora ohioensis complex, – Isospora canis

The treatment limits the spread of Isospora but is not effective against the appearance of clinical signs in infected animals.


CONTRAINDICATIONS

Do not use in dogs / puppies under 2 weeks of age or weighing less than 0.4 kg. Do not use in case of hypersensitivity to the active substances or any of the excipients.


URGENT REACTIONS

Frequency of adverse reactions is defined by the following classification:

– very common (more than 1 in 10 animals experiencing adverse reactions during the course of one treatment)

– common (more than 1 but less than 10 animals per 100 animals)

– uncommon (more than 1 but less than 10 animals per 1,000 animals)

– rare (more than 1 but less than 10 animals per 10,000 animals)

– very rare (less than 1 animal in 10,000 animals, including isolated messages)


TYPES OF ANIMALS FOR WHICH THE VMP IS INTENDED

Dogs.


DOSAGE FOR EACH SPECIES, ROUTE (S) AND METHOD OF ADMINISTRATION

For oral use in dogs from two weeks of age and weighing at least 0.4 kg.

Dosage and course of treatment:

The minimum recommended dose is 0.5 ml / kg of body weight (w / w), which corresponds to 0.45 mg emodepside / kg body weight. And 9 mg toltrazuril / kg body weight. The recommended doses are shown in the table below:


 

Weight (kg)
Dose (ml)
0.4 0.2
0.4 – 0.6 0.3
0.6 – 0.8 0.4
0.8 – 1.0 0.5
1.0 – 1.2 0.6
1.2 – 1.4 0.7
1.4 – 1.6 0.8
1.6 – 1.8 0.9
1.8 – 2.0 1.0
2.0 – 2.2 1.1
2.2 – 2.4 1.2
2.4 – 2.6 1.3
2.6 – 2.8 1.4
2.8 – 3.0 1.5
3.0 – 3.2 1.6
3.2 – 3.4 1.7
3.4 – 3.6 1.8
3.6 – 3.8 1.9
3.8 – 4.0 2.0
4 – 5 2.5
5 – 6 3.0
6 – 7 3.5
7 – 8 4.0
8 – 9 4.5
9 – 10 5.0
                                                                      Over 10kg Extend with 0.5ml / kg of body weight


ADVICE ON CORRECT ADMINISTRATION

1.Grow well before use.

2. Place the syringe tip tightly into the bottle opening.

3. Turn the bottle upside-down and pull out the required volume.

4. Apply Procox to the dog’s mouth.



Special warnings for each type of animal for which the VMP is intended


Treatment prevents the spread of Isospora infection but is not effective against symptoms (eg diarrhea) in already infected animals. It may be necessary to appoint maintenance treatment (from veterinary

Physician) in animals with diarrhea. Isospora oocysts are resistant to many disinfectants and can survive for a long time in the surrounding environment. Rapid removal of stools before sporulation of oocysts (within 12 hours) reduces the likelihood of transmission of the infection. All dogs in the group threatened by infection should be treated at the same time.



Special precautions for use in animals

It is not recommended to use Procox in cats or related breeds, carriers or suspected to carry mdr1 mutation – / – because the tolerance to the product in puppies carrying mdr1 mutation – / – is shown to be lower than that of other cats. As with any antiparasitic product, frequent and prolonged use may cause development of resistance. An appropriate course of treatment prescribed by a veterinarian will ensure adequate parasite control and reduce the likelihood of resistance. There is limited experience in severely exhausted dogs and in dogs with severely impaired kidney or liver function. Please tell your veterinarian if your dog suffers from any of these conditions.


Pregnancy and lactation

The safety of the veterinary medicinal product has not been established during pregnancy

Lactation. It is not recommended to use during the whole pregnancy and through

The first two weeks of lactation.

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